Lancaster City boss Darren Peacock and his assistant Trevor Sinclair have left the club by mutual consent.
The high-profile pair are understood to have departed Giant Axe after a meeting with club chiefs on Monday morning.
Their final game in charge was the 2-0 defeat at Droylsden in the second qualifying round of the FA Cup on Saturday.
Peacock said: “It was a five-year plan but I feel I’ve taken the club as far as I can given the financial restraints and other things at the club.
“I’ve really enjoyed it but it has been frustrating at times.
“We’ve been quite far apart on a few ideas and I felt it was time to move on.”
Former Newcastle, Blackburn and Queens Park Rangers defender Peacock was a surprise appointment at the club when he took his first managerial job in April 2013.
Ex-England international Sinclair became the second high-profile figure at Giant Axe when he arrived to be Peacock’s number two in July 2014.
Last season they guided the Dolly Blues to 11th in the Evo-Stik First Division North but have endured a tough start to the new season culminating in the FA Cup exit on Saturday.
In a statement, Lancaster City said: “The club would like to express their appreciation for the time and effort Darren has put into the job, which was way beyond normally expected of managers at this level, and he has never been less than thoroughly professional in his approach, despite our modest budget.
“We wish Darren all the best in his future endeavours.”