Jim Bentley said it was a case of the "same old story" as his Morecambe side collapsed to defeat at Bristol Rovers on Saturday.
Jamie Devitt's penalty had put The Shrimps in control but 12 second-half minutes saw goals from Rory Gaffney and Billy Bodin, followed by Andy Fleming's red card for pulling back Stuart Sinclair's hair, turn the game on its head.
Bentley said: "It's the same story every week.
"It's so frustrating and it's absolutely destroying me to be honest.
"We had the wind in our faces in the first half but didn't put a foot wrong to be honest.
"The crowd booed them off because we were in the lead and deservingly so.
"They upped the tempo after the break which they're going to attacking the home end but I didn't feel we were in danger.
"No-one made a mistake, we defended well as a group and looked a threat on the break.
"We even had good opportunities to go 2-0 up and the keeper's made a couple of good saves.
"But then we were punished for our first mistake. Barry Roche has been excellent for us but he’ll be disappointed. It looked easier to catch it but he’s punched it straight at the feet of Gaffney who's put it away.
"Then they've got the momentum and got the second and soon after we're down to 10 men. Whether it's ill discipline or not I'll have to see it again.
"Everything we seem to be doing wrong is getting punished at the moment. We're not a bad side."